Got my shot

[jimnyc]

So got my shot at 2pm, all fine for 5 minutes, then slightly light headed feeling and that was it til I left. Still a tad weird feeling, but no pain in the arm, no headache and no other symptoms. Probably light headed from coffee and no food!

Hopefully I won't develop a headache or fever. I can deal with the fever but tired of headaches.

And all they give you is a lame card? No signature? No raised stamp? Just a plain card from the CDC with my name filled in with pen and date & Pfizer vaccine. But no signature or anything like that. No wonder these idiots are worried about fraud, I could have made this card identically with a proper printer and card paper.

Now go back on the 18th for #2. :thumb:

[Tyr-Ziu Saxnot]

So got my shot at 2pm, all fine for 5 minutes, then slightly light headed feeling and that was it til I left. Still a tad weird feeling, but no pain in the arm, no headache and no other symptoms. Probably light headed from coffee and no food!

Hopefully I won't develop a headache or fever. I can deal with the fever but tired of headaches.

And all they give you is a lame card? No signature? No raised stamp? Just a plain card from the CDC with my name filled in with pen and date & Pfizer vaccine. But no signature or anything like that. No wonder these idiots are worried about fraud, I could have made this card identically with a proper printer and card paper.

Now go back on the 18th for #2. :thumb:

You will let us know if by this coming weekend, you start growing a third arm , eye or ear..- :laugh:--Tyr

[jimnyc]

You will let us know if by this coming weekend, you start growing a third arm , eye or ear..- :laugh:--Tyr

Will do my friend! About as unsure here with things as you are but felt as if I needed it to travel to see Dad and other requirements. Was not thrilled and was nervous as hell for that 15 minutes and especially when I first got that weirdish feeling, thinking that well, here it comes, I'm a goner!

[Tyr-Ziu Saxnot]

Not sure what pull I have but I just said a prayer for you my friend.
Never know, but just might help and surely cannot hurt..-Tyr

[jimnyc]

Not sure what pull I have but I just said a prayer for you my friend.
Never know, but just might help and surely cannot hurt..-Tyr

Appreciated! Hopefully all fine now that the first 15-30 were no issue. All symptoms perfect right now and no ill effects and feel great - so hopefully it'll stay that way.

[Abbey Marie]

Russ just had his 2nd yesterday, and a few hours later experienced some chills and a very slight fever. Today he feels lethargic. Moderna for him.

Feel better!

[Kathianne]

I know some don't trust the vax and I respect their choice. That it was just like the flu though? Not so sure that's the case, especially for the most vulnerable.

India has vaccine, just not enough, certainly not for neighbors:

https://hotair.com/allahpundit/2021/04/30/indian-doctor-what-were-experiencing-here-with-covid-is-an-apocalypse-n386996

[jimnyc]

I know some don't trust the vax and I respect their choice. That it was just like the flu though? Not so sure that's the case, especially for the most vulnerable.

India has vaccine, just not enough, certainly not for neighbors:

https://hotair.com/allahpundit/2021/04/30/indian-doctor-what-were-experiencing-here-with-covid-is-an-apocalypse-n386996

I wouldn't want to be there on normal days for medical care - but I saw a few videos and it's insanity over there over this pandemic.

I saw people at a hospital in horrible shape, and literally being denied entrance and physically forced away. And they are apparently all like that now. But even folks inside are often getting shitty treatment and a lack of oxygen supplies.

Uggghhhh, then I saw quite a few places running as crematoriums. And by that, I mean like Game of Thrones and laying down about 100 stacks of wood, putting each on one and lighting up. Repeat and rinse process. And the majority that such places weren't wearing masks while handling the wood/fire/bodies/sheets and more.

[Kathianne]

I wouldn't want to be there on normal days for medical care - but I saw a few videos and it's insanity over there over this pandemic.

I saw people at a hospital in horrible shape, and literally being denied entrance and physically forced away. And they are apparently all like that now. But even folks inside are often getting shitty treatment and a lack of oxygen supplies.

Uggghhhh, then I saw quite a few places running as crematoriums. And by that, I mean like Game of Thrones and laying down about 100 stacks of wood, putting each on one and lighting up. Repeat and rinse process. And the majority that such places weren't wearing masks while handling the wood/fire/bodies/sheets and more.

We're fortunate. Most people have adequate food, etc. Once they got the vaccine it was distributed asap and keeps going faster. Have enough to share. So yes, some will be fine, even better off if herd immunity is reached. They have a choice.

[jimnyc]

So yes, some will be fine, even better off if herd immunity is reached. They have a choice.

Remember how much we discussed herd immunity for awhile there in the beginning? Then what? Then came Fauci and others and that whole thing seemed to go out the window and some even dismissed it. Look at Rand Paul and read all his comments over time. Read various doctors who don't have a political stake in this and/or don't care about politics and towing the line. And hell, we even knew about it.

[Mr. P]

Two mice are in a bar having a beer..

The 1st mouse asks the 2nd..."so are you getting the vaccine?".

The 2nd mouse says..."Oh HELL NO, They haven't completed the testing on the humans yet!".:laugh:

I feel the same.

Just sayin

[jimnyc]

Two mice are in a bar having a beer..

The 1st mouse asks the 2nd..."so are you getting the vaccine?".

The 2nd mouse says..."Oh HELL NO, They haven't completed the testing on the humans yet!".:laugh:

I feel the same.

Just sayin

:laugh2::laugh2:

That made me laugh out loud! And truth-ness to it, as I think some steps in producing and testing these vaccines were ignored/bypassed or whatever you want to call it. There's a reason why the length of years go into the process and getting FDA approval.

Someone let the mice know if I should croak! https://i.imgur.com/OZjYE1B.png

[fj1200]

There's a reason why the length of years go into the process and getting FDA approval.

Yah. Onerous regulations.

[Bilgerat]

Two mice are in a bar having a beer..

The 1st mouse asks the 2nd..."so are you getting the vaccine?".

The 2nd mouse says..."Oh HELL NO, They haven't completed the testing on the humans yet!".:laugh:

I feel the same.

Just sayin


Alls I know is, I'm taking my shots :laugh2::laugh2:

https://scontent-mia3-2.xx.fbcdn.net/v/t1.6435-9/182575699_10160122660523455_3095417823031444698_n. jpg?_nc_cat=103&ccb=1-3&_nc_sid=730e14&_nc_ohc=263k0rfXK-IAX9Ydf4P&_nc_ht=scontent-mia3-2.xx&oh=da84aa305b4ed9bc2de700ef07dcb041&oe=60B75B86

[jimnyc]

My wife got her 2nd shot (pfizer) yesterday at 3pm. Like the first, she got a bad vertigo vibe throughout the eve and didn't feel the greatest. But took a turn towards hell overnight like I did with my first. She was truly sick this morn and in tears. She's not too good with medications and avoids them like the plague. She did ultimately take a few Tylenol, and I shoved water on her to keep from dehydration. But you can tell it took it all out of her and she's got no energy and feels like the flu, but she has no temperature.

[Gunny]

Argument is moot when one's choice is dictated by the needs of others.
Got my 1st shot. Feltike I was trying to catch the flu for a day. Arm celt like it had a deep bruise for several days. I've had worse.

[jimnyc]

Argument is moot when one's choice is dictated by the needs of others.
Got my 1st shot. Feltike I was trying to catch the flu for a day. Arm celt like it had a deep bruise for several days. I've had worse.

I'm nervous as hell now for my 2nd shot on the 18th. Seems many got a reaction on the first shot and those that did were all similar, and those that did got a similar but worse reaction with the 2nd. So I'm going to bed that evening with 3 tylenol and 3 ibuprofen in my blood and maybe an oxycodone if I had one, and imitrex by my side along with other stuff.

[Abbey Marie]

I'm nervous as hell now for my 2nd shot on the 18th. Seems many got a reaction on the first shot and those that did were all similar, and those that did got a similar but worse reaction with the 2nd. So I'm going to bed that evening with 3 tylenol and 3 ibuprofen in my blood and maybe an oxycodone if I had one, and imitrex by my side along with other stuff.

Jim, research taking Ibuprofen first. I’ve heard not to take it.

[jimnyc]

Jim, research taking Ibuprofen first. I’ve heard not to take it.

Really? I usually take Advil but as of late a monster bottle of ibuprofen from Amazon, and was Kirkland from Costco for awhile. (both generic and just cheaper). Had no idea it had anything negative about it, but gonna look it up. Yikes!

[jimnyc]

So still have to dig in and read, but first search lead to a bunch of articles and here are just a few...


11 reasons to avoid ibuprofen

As if we needed another reason to question taking non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, a new study has concluded that taking these drugs increases the risk of cardiac arrest by a whopping 31 percent. A cardiac arrest is a serious medical emergency as the heart stops pumping blood throughout the body.

The study was based on the analysis of 28,947 cardiac patients in Denmark, and was published in the European Heart Journal.

“Our findings support the accumulating evidence of an unfavourable cardiovascular risk profile associated with use of the non-selective NSAIDs. This calls for special awareness in order to balance risks against benefits in treatment with NSAIDs,” the researchers concluded.

Despite this and other warnings, NSAIDs remain the most commonly used and abused drugs, typically for pain. They are particularly dangerous because they are widely available over the counter and because their use is typically considered benign both by consumers and medical professionals. Thirty-three million Americans regularly use NSAIDs, with millions others worldwide. In fact, many people, especially athletes, include them in their daily routines the same way they do dietary supplements.

But these drugs are far from benign. There are many common problems and side-effects associated with their use. In addition to increased cardiac risk, consider these other issues associated with the use of NSAIDs:


In addition to cardiac arrest, NSAIDs are associated with other heart issues such as increased risk of atrial fibrillation or heart flutter.
These drugs may delay healing.
NSAIDs disrupt the body’s own anti-inflammatory system. While reducing certain molecules responsible for inflammation, natural anti-inflammatory molecules also are impaired.
About 16,500 people annually die due to NSAIDs use. The culprit is usually ulcer-related complications associated with the drug’s continued use.
Intestinal problems, including bleeding, occur in almost everyone taking NSAIDs (even if it’s not noticeable). This can lead to anemia and fatigue.
Muscle dysfunction, contributing to physical aches and pains, and injuries is often prevalent among NSAIDs users.
NSAIDs can reduce the body’s ability to repair joint and bone stress.
Increased risk of kidney damage, especially when you’re dehydrated, can result from taking NSAIDs.
NSAIDs can disturb sleep.
Immune system stress often accompanies NSAIDs use.


For certain, no injury or inflammatory condition is caused by a drug deficiency. Before reaching for a magic pill to cure your pain, consider the cause of the problem and seek out more natural choices for remedies, especially balancing fat and eating certain foods.

https://philmaffetone.com/11-reasons-avoid-ibuprofen/


DOCTORS TELL PEOPLE OVER 40 TO STOP TAKING IBUPROFEN! HERE’S WHY!

ibuprofen FI
DOCTORS TELL PEOPLE OVER 40 TO STOP TAKING IBUPROFEN! HERE’S WHY!
FEATUREDHEALTH & LONGEVITYLIFESTYLEREMEDIESRESEARCHSAFETY 1
When you’ve got a headache or back soreness, what do you do? If you’re like many Americans, you probably reach for a bottle of ibuprofen (trade name Advil).

It can seem like a real elixir, taking away any trace of pain in a flash.

But is it really safe?

Don’t let the over-the-counter status of ibuprofen fool you. There are some real serious risks associated with even casual use of the drug.

Of those risks, one of the most concerning is the potential for heart damage.

Even The FDA Is Warning You

Back in 2005, the FDA issued a warning about ibuprofen, saying it significantly increases one’s risk of heart attack or stroke. Well just last year, they made the decision to strengthen this warning.

The FDA rarely does this. But after an extensive review of the drug, they issued they following statements:

Even with short term use, one’s heart attack and stroke risk increase significantly.
This risk increases the longer one continues to use ibuprofen.
You do not need to have an existing heart condition to be at risk, although such a condition does increase your chances.
These risks make ibuprofen especially dangerous to individuals over 40 – the age at which one’s risk of heart disease begins to skyrocket.

Keep in mind that the FDA approves of some pretty terrible medications, but even they are raising a red flag when it comes to this over the counter drug.

Don’t Be Misled
The major problem with over-the-counter medications like ibuprofen – or acetaminophen, for that matter – is that people generally assume they pose no major risk.

A prescription is seen as an indicator of seriousness. In its absence, most people just shrug and pop pills whenever they even think they need to.

Hopefully the information I shared in this post changes your mind in that regard.

Don’t worry – I’m not just going to leave you hanging without at least one alternative option for pain relief.

Rest - https://www.davidwolfe.com/doctors-tell-over-40-stop-ibuprofen/


Top Doctors Are Warning Anyone Over 40 To Stop Taking Ibuprofen Immediately. Here’s Why…

https://dailyhealthpost.com/stop-taking-ibuprofen/

[jimnyc]

---

Ibuprofen: 7 things you should know

1. How it works


Ibuprofen helps to relieve pain and inflammation by blocking the effects of cyclooxygenase (COX) enzymes. This prevents prostaglandin synthesis (prostaglandins elevate body temperature and make nerve endings more sensitive to pain transmission).
Ibuprofen belongs to a group of medicines known as NSAIDs (nonsteroidal anti-inflammatory drugs).


2. Upsides


Effective for the relief of minor aches and pains due to arthritis, backache, the common cold, headache and migraine, menstruation, muscular aches, and toothache in adults.
Relieves minor aches and pain in children aged 6 months or older.
Temporarily relieves fever.
Does not cause dependence and is readily available at a low cost.
The incidence of stomach-related side effects is about half that seen with aspirin or indomethacin when ibuprofen is used at low dosages. However, this benefit is lost with higher dosages.
Available as tablets, capsules, chewable tablets, suspension, and in an injectable form.
Widely available over-the-counter.
Generic ibuprofen is available.


3. Downsides

If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include:


Stomach-related side effects including indigestion, heartburn, and bleeding. People of an older age, taking other medicines that affect the stomach, or who drink more than 3 glasses of alcohol per day may be more at risk. Ibuprofen has one of the lowest risks of stomach-related side effects compared with other NSAIDs.
Most NSAIDs have been associated with an increased risk of stroke or heart attack. The risk may be higher in patients with pre-existing cardiovascular conditions and with dosages of ibuprofen greater than 1200mg per day.
May require three to four times daily dosing because of short duration of acton.
May not be suitable for some people including those with kidney disease, a history of stomach ulcers or other gastrointestinal disorders, with pre-existing cardiovascular disease, or following coronary artery bypass graft surgery.
May interact with some other medicines such as warfarin, SSRIs, ACE inhibitors, and diuretics.


Note: In general, seniors or children, people with certain medical conditions (such as liver or kidney problems, heart disease, diabetes, seizures) or people who take other medications are more at risk of developing a wider range of side effects. View complete list of side effects

4. Bottom Line

Ibuprofen is effective for the short-term relief of minor aches and pains. Risk of stomach-related side effects is about half that seen with aspirin although the risk increases with higher dosages and a longer duration of use.

5. Tips


Take with food or milk if stomach disturbances (such as indigestion) occur with use. See a doctor if these persist.
Always use the lowest effective dose for the shortest duration consistent with the condition being treated.
If you are taking ibuprofen and find it is not working very well for you, you may like to try a different NSAID.
Response to different NSAIDs can vary so switching types (for example, from ibuprofen to naproxen) may improve response.
See a doctor immediately if you experience any difficulty with breathing, unexplained sickness or fatigue, loss of appetite, vision changes, fluid retention or abnormal bleeding.
NSAIDs should not be used in the last 3 months of pregnancy; ask your doctor before using any medication during pregnancy.
Avoid ibuprofen if you have a history of asthma or hives due to aspirin use or other NSAIDs, like naproxen.
Do not use this medicine if you have just had heart bypass surgery (also called coronary artery bypass graft, or CABG).


6. Response and Effectiveness


Peak levels of ibuprofen are reached 1-2 hours after administration.
Equally effects COX-1 and COX-2 enzymes.


7. Interactions

Medicines that interact with ibuprofen may either decrease its effect, affect how long it works for, increase side effects, or have less of an effect when taken with ibuprofen. An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. Speak to your doctor about how drug interactions should be managed.

Common medications that may interact with ibuprofen include:


ACE inhibitors or ARBs, such as captopril, enalapril, or losartan
antibiotics, such as ciprofloxacin or vancomycin
anticoagulants (blood thinners) such as apixaban, dabigatran, fondaparinux, heparin, or warfarin
antidepressants, such as citalopram, escitalopram, fluoxetine, or paroxetine
antifungals, such as voriconazole
antiplatelets, such as clopidogrel or ticagrelor
beta-blockers, such as acebutolol, atenolol, bisoprolol, or carvedilol
bisphosphonates, such as alendronate
corticosteroids, such as dexamethasone or prednisone
digoxin
diuretics (water pills), such as chlorthalidone, chlorothiazide, hydrochlorothiazide (HCTZ), or furosemide
glucagon
haloperidol
HIV medications (eg, Stribild, tenofovir)
metformin
other nonsteroidal anti-inflammatories (NSAIDs), such as celecoxib, diclofenac, etodolac, ketorolac, meloxicam, nabumetone, or naproxen
sulfonylureas (a type of diabetes medication), such as glimepiride, glyburide, or glipizide
supplements, such as glucosamine, omega-3 fatty acids, vitamin E
others, such as cyclosporine, lithium, methotrexate, pemetrexed, pirfenidone, or tacrolimus.


Drinking alcohol while taking ibuprofen may increase the risk of gastrointestinal-related side effects or kidney damage.

Note that this list is not all-inclusive and includes only common medications that may interact with ibuprofen. You should refer to the prescribing information for ibuprofen for a complete list of interactions.

https://www.drugs.com/tips/ibuprofen-patient-tips


And then even though there is this - I still don't feeel comfy in this little time, so no more for me. Tylenol and Imitrex it is.

Here’s What We Know About Ibuprofen and COVID-19


Experts say there’s no clear evidence that ibuprofen makes COVID-19 worse.
One thing specific to COVID-19 is that some lab experiments are showing that ibuprofen may boost the amount of ACE2 receptors that the virus uses to infect cells and could make the virus spread faster.
But that’s just theoretical.


The World Health Organization (WHO) has changed its stance on taking ibuprofen if you have COVID-19, but people are still scratching their heads over what they should take if or when they contract the virus.

After previously announcing that people with the virus shouldn’t take ibuprofen to treat pain and fever, the WHO now says they don’t advise against it.

The flip-flopping has a lot of people confused — especially those stocking up on medication in anticipation of getting the virus.

Dr. Otto O. Yang, a professor of medicine in the infectious diseases division at the David Geffen School of Medicine at UCLA, told Healthline there’s no evidence that ibuprofen causes worsening of COVID-19, “although there is circulating misinformation to that effect.”

Fever (medication) frenzy

The concern began after a study in The LancetTrusted Source stated that ibuprofen boosts the angiotensin-converting enzyme 2 (ACE2), which may facilitate and worsen COVID-19. As a result, WHO originally warned most patients to stick with acetaminophen, which is also known as paracetamol or Tylenol.

Patients likely have increased ACE2 expression if they’re treated with ACE inhibitors, angiotensin II type I receptor blockers (ARBs), or thiazolidinediones, the report noted. Those drugs are commonly taken by those with cardiovascular disease, hypertension, and diabetes. Ibuprofen can also increase ACE2, the study noted.

Anti-inflammatory drugs and COVID-19

The notion that anti-inflammatory drugs increase the risk of complications during fever or infection is “mostly theoretical,” Yang said.

Medical experts debate whether or not reducing the inflammation that causes fever and muscle ache actually lowers the effectiveness of the immune response. On the flip side, patients who have worse symptoms may be more likely to take ibuprofen, and their outcome may have nothing to do with the medication itself.

“There are some clinical observations of small numbers of patients that suggest ibuprofen could slow recoveryTrusted Source from bacterial pneumonias or make some viral infections like chickenpox more severe, but these aren’t careful prospective scientific studies,” Yang said.

“Other publications have even argued that ibuprofen can be helpful in lung infectionsTrusted Source by reducing the amount of inflammation, which may be damaging to the lung,” he added.

One thing specific to COVID-19 is that some lab experiments are showing that ibuprofen may boost the amount of ACE2 receptors that the virus uses to infect cells and could make the virus spread faster. But that is “purely theory that so far is not backed by clinical evidence in patients,” Yang said.

It’s unclear if what has been seen in the lab translates to the clinic, Yang added.

For example, ibuprofen may increase the ACE2 level in cells. “But that may be meaningless in a person if that increase is small, or if there is already so much receptor that adding more doesn’t matter,” Yang explained.

Evidence lacking

There’s not enough evidence to show that ibuprofen could make COVID-19 worse, Rodney E. Rohde, PhD, a professor at Texas State University, told Healthline.

“I do not believe there is enough evidence due to a small sample size of patients,” he said. “However, if one is concerned, then they may want to avoid those drugs or drug families.”

Rohde explained that ibuprofen is known to diminish the response of the body’s immune system. The inflammatory process is a vital component of the overall immune response, especially the second line of defense that triggers many third-line defense mechanisms, such as T and B cell responses, he said.

For now, Rohde said there’s “no hard evidence” not to take over-the-counter or prescription pain medications. That said, Rohde advises people to talk to their doctors for more recommendations based on their individual health.

As for the National Institute of Allergy and Infectious Diseases, it gave a statement to Healthline and suggested people reach out to the Centers for Disease Control and Prevention (CDC) for updated COVID-19 treatment guidelines. “More research is needed to evaluate reports that ibuprofen and other over-the-counter anti-inflammatory drugs may affect the course of COVID-19,” it said.

“Currently, there is no conclusive evidence that ibuprofen and other over-the-counter anti-inflammatory drugs increases the risk of serious complications or of acquiring the virus that causes COVID-19. There is also no conclusive evidence that taking over-the-counter anti-inflammatory drugs is harmful for other respiratory infections.”

https://www.healthline.com/health-news/what-to-know-about-ibuprofen-and-covid-19

[Gunny]

I'm nervous as hell now for my 2nd shot on the 18th. Seems many got a reaction on the first shot and those that did were all similar, and those that did got a similar but worse reaction with the 2nd. So I'm going to bed that evening with 3 tylenol and 3 ibuprofen in my blood and maybe an oxycodone if I had one, and imitrex by my side along with other stuff.I keep hearing the 2nd shot is worse. Hair didn't start growing out of my palms with the first, so we'll see :)

I take ibuprofen. The government warns you not take it but hands it out like candy because they won't give anything else that works. The government hates not controlling every aspect of our lives, to include pain, while abusers give the government every excuse to do so.

[jimnyc]

I keep hearing the 2nd shot is worse. Hair didn't start growing out of my palms with the first, so we'll see :)

I take ibuprofen. The government warns you not take it but hands it out like candy because they won't give anything else that works. The government hates not controlling every aspect of our lives, to include pain, while abusers give the government every excuse to do so.

Just caught me off guard was all. I am forever taking tylenol and ibuprofen and even Aleve when others not around.

[Abbey Marie]

Just caught me off guard was all. I am forever taking tylenol and ibuprofen and even Aleve when others not around.

My Cardiologist told me to try to not take it ever since my heart attack. She didn’t strictly rule it out, but I take Tylenol for everything except a bad headache. Then I will still take a couple of Advil, as I HATE headaches.

But I was referring strictly to taking it right before or after your shot, as I’d heard it reduces the efficacy of the shot.

[SassyLady]

I never take ibuprofen. Acetaminophen is my drug of choice for pain. Used it after surgery instead of painkillers.

[fj1200]

So got my shot at 2pm...

Mine today at 11:00. So far so good.

[Abbey Marie]

Mine today at 11:00. So far so good.

Fevers, etc., generally take at least 7 hours to manifest, but can take longer. Which version did you get?

[fj1200]

Fevers, etc., generally take at least 7 hours to manifest, but can take longer. Which version did you get?

Pfizer. 6 hours and counting and all's well.

For the shingles vaccine I only felt some side effects on the second dose and that was very short term. Hopefully no worse for this one.

[jimnyc]

Fevers, etc., generally take at least 7 hours to manifest, but can take longer. Which version did you get?

That's how it was for me. I only had a vertigo/tunnel vision thing on and off from shot time til I went to bed and woke at like 4am in bad shape. I got my shot at 4pm, so ya see the timeline for me.


Pfizer. 6 hours and counting and all's well.

For the shingles vaccine I only felt some side effects on the second dose and that was very short term. Hopefully no worse for this one.

Glad to see you survived! Now you're on the list like a few of us, wondering if we will be dead in 2 years or not. :dunno:

I got the flu a few times after the flu shot but nothing really lasting. No other reactions to anything. 'Cept this thing, leaving me wishing for death. https://i.imgur.com/qtJQFVu.jpg

[Evmetro]

---

Ibuprofen: 7 things you should know

1. How it works


Ibuprofen helps to relieve pain and inflammation by blocking the effects of cyclooxygenase (COX) enzymes. This prevents prostaglandin synthesis (prostaglandins elevate body temperature and make nerve endings more sensitive to pain transmission).
Ibuprofen belongs to a group of medicines known as NSAIDs (nonsteroidal anti-inflammatory drugs).


2. Upsides


Effective for the relief of minor aches and pains due to arthritis, backache, the common cold, headache and migraine, menstruation, muscular aches, and toothache in adults.
Relieves minor aches and pain in children aged 6 months or older.
Temporarily relieves fever.
Does not cause dependence and is readily available at a low cost.
The incidence of stomach-related side effects is about half that seen with aspirin or indomethacin when ibuprofen is used at low dosages. However, this benefit is lost with higher dosages.
Available as tablets, capsules, chewable tablets, suspension, and in an injectable form.
Widely available over-the-counter.
Generic ibuprofen is available.


3. Downsides

If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include:


Stomach-related side effects including indigestion, heartburn, and bleeding. People of an older age, taking other medicines that affect the stomach, or who drink more than 3 glasses of alcohol per day may be more at risk. Ibuprofen has one of the lowest risks of stomach-related side effects compared with other NSAIDs.
Most NSAIDs have been associated with an increased risk of stroke or heart attack. The risk may be higher in patients with pre-existing cardiovascular conditions and with dosages of ibuprofen greater than 1200mg per day.
May require three to four times daily dosing because of short duration of acton.
May not be suitable for some people including those with kidney disease, a history of stomach ulcers or other gastrointestinal disorders, with pre-existing cardiovascular disease, or following coronary artery bypass graft surgery.
May interact with some other medicines such as warfarin, SSRIs, ACE inhibitors, and diuretics.


Note: In general, seniors or children, people with certain medical conditions (such as liver or kidney problems, heart disease, diabetes, seizures) or people who take other medications are more at risk of developing a wider range of side effects. View complete list of side effects

4. Bottom Line

Ibuprofen is effective for the short-term relief of minor aches and pains. Risk of stomach-related side effects is about half that seen with aspirin although the risk increases with higher dosages and a longer duration of use.

5. Tips


Take with food or milk if stomach disturbances (such as indigestion) occur with use. See a doctor if these persist.
Always use the lowest effective dose for the shortest duration consistent with the condition being treated.
If you are taking ibuprofen and find it is not working very well for you, you may like to try a different NSAID.
Response to different NSAIDs can vary so switching types (for example, from ibuprofen to naproxen) may improve response.
See a doctor immediately if you experience any difficulty with breathing, unexplained sickness or fatigue, loss of appetite, vision changes, fluid retention or abnormal bleeding.
NSAIDs should not be used in the last 3 months of pregnancy; ask your doctor before using any medication during pregnancy.
Avoid ibuprofen if you have a history of asthma or hives due to aspirin use or other NSAIDs, like naproxen.
Do not use this medicine if you have just had heart bypass surgery (also called coronary artery bypass graft, or CABG).


6. Response and Effectiveness


Peak levels of ibuprofen are reached 1-2 hours after administration.
Equally effects COX-1 and COX-2 enzymes.


7. Interactions

Medicines that interact with ibuprofen may either decrease its effect, affect how long it works for, increase side effects, or have less of an effect when taken with ibuprofen. An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. Speak to your doctor about how drug interactions should be managed.

Common medications that may interact with ibuprofen include:


ACE inhibitors or ARBs, such as captopril, enalapril, or losartan
antibiotics, such as ciprofloxacin or vancomycin
anticoagulants (blood thinners) such as apixaban, dabigatran, fondaparinux, heparin, or warfarin
antidepressants, such as citalopram, escitalopram, fluoxetine, or paroxetine
antifungals, such as voriconazole
antiplatelets, such as clopidogrel or ticagrelor
beta-blockers, such as acebutolol, atenolol, bisoprolol, or carvedilol
bisphosphonates, such as alendronate
corticosteroids, such as dexamethasone or prednisone
digoxin
diuretics (water pills), such as chlorthalidone, chlorothiazide, hydrochlorothiazide (HCTZ), or furosemide
glucagon
haloperidol
HIV medications (eg, Stribild, tenofovir)
metformin
other nonsteroidal anti-inflammatories (NSAIDs), such as celecoxib, diclofenac, etodolac, ketorolac, meloxicam, nabumetone, or naproxen
sulfonylureas (a type of diabetes medication), such as glimepiride, glyburide, or glipizide
supplements, such as glucosamine, omega-3 fatty acids, vitamin E
others, such as cyclosporine, lithium, methotrexate, pemetrexed, pirfenidone, or tacrolimus.


Drinking alcohol while taking ibuprofen may increase the risk of gastrointestinal-related side effects or kidney damage.

Note that this list is not all-inclusive and includes only common medications that may interact with ibuprofen. You should refer to the prescribing information for ibuprofen for a complete list of interactions.

https://www.drugs.com/tips/ibuprofen-patient-tips


And then even though there is this - I still don't feeel comfy in this little time, so no more for me. Tylenol and Imitrex it is.

Here’s What We Know About Ibuprofen and COVID-19


Experts say there’s no clear evidence that ibuprofen makes COVID-19 worse.
One thing specific to COVID-19 is that some lab experiments are showing that ibuprofen may boost the amount of ACE2 receptors that the virus uses to infect cells and could make the virus spread faster.
But that’s just theoretical.


The World Health Organization (WHO) has changed its stance on taking ibuprofen if you have COVID-19, but people are still scratching their heads over what they should take if or when they contract the virus.

After previously announcing that people with the virus shouldn’t take ibuprofen to treat pain and fever, the WHO now says they don’t advise against it.

The flip-flopping has a lot of people confused — especially those stocking up on medication in anticipation of getting the virus.

Dr. Otto O. Yang, a professor of medicine in the infectious diseases division at the David Geffen School of Medicine at UCLA, told Healthline there’s no evidence that ibuprofen causes worsening of COVID-19, “although there is circulating misinformation to that effect.”

Fever (medication) frenzy

The concern began after a study in The LancetTrusted Source stated that ibuprofen boosts the angiotensin-converting enzyme 2 (ACE2), which may facilitate and worsen COVID-19. As a result, WHO originally warned most patients to stick with acetaminophen, which is also known as paracetamol or Tylenol.

Patients likely have increased ACE2 expression if they’re treated with ACE inhibitors, angiotensin II type I receptor blockers (ARBs), or thiazolidinediones, the report noted. Those drugs are commonly taken by those with cardiovascular disease, hypertension, and diabetes. Ibuprofen can also increase ACE2, the study noted.

Anti-inflammatory drugs and COVID-19

The notion that anti-inflammatory drugs increase the risk of complications during fever or infection is “mostly theoretical,” Yang said.

Medical experts debate whether or not reducing the inflammation that causes fever and muscle ache actually lowers the effectiveness of the immune response. On the flip side, patients who have worse symptoms may be more likely to take ibuprofen, and their outcome may have nothing to do with the medication itself.

“There are some clinical observations of small numbers of patients that suggest ibuprofen could slow recoveryTrusted Source from bacterial pneumonias or make some viral infections like chickenpox more severe, but these aren’t careful prospective scientific studies,” Yang said.

“Other publications have even argued that ibuprofen can be helpful in lung infectionsTrusted Source by reducing the amount of inflammation, which may be damaging to the lung,” he added.

One thing specific to COVID-19 is that some lab experiments are showing that ibuprofen may boost the amount of ACE2 receptors that the virus uses to infect cells and could make the virus spread faster. But that is “purely theory that so far is not backed by clinical evidence in patients,” Yang said.

It’s unclear if what has been seen in the lab translates to the clinic, Yang added.

For example, ibuprofen may increase the ACE2 level in cells. “But that may be meaningless in a person if that increase is small, or if there is already so much receptor that adding more doesn’t matter,” Yang explained.

Evidence lacking

There’s not enough evidence to show that ibuprofen could make COVID-19 worse, Rodney E. Rohde, PhD, a professor at Texas State University, told Healthline.

“I do not believe there is enough evidence due to a small sample size of patients,” he said. “However, if one is concerned, then they may want to avoid those drugs or drug families.”

Rohde explained that ibuprofen is known to diminish the response of the body’s immune system. The inflammatory process is a vital component of the overall immune response, especially the second line of defense that triggers many third-line defense mechanisms, such as T and B cell responses, he said.

For now, Rohde said there’s “no hard evidence” not to take over-the-counter or prescription pain medications. That said, Rohde advises people to talk to their doctors for more recommendations based on their individual health.

As for the National Institute of Allergy and Infectious Diseases, it gave a statement to Healthline and suggested people reach out to the Centers for Disease Control and Prevention (CDC) for updated COVID-19 treatment guidelines. “More research is needed to evaluate reports that ibuprofen and other over-the-counter anti-inflammatory drugs may affect the course of COVID-19,” it said.

“Currently, there is no conclusive evidence that ibuprofen and other over-the-counter anti-inflammatory drugs increases the risk of serious complications or of acquiring the virus that causes COVID-19. There is also no conclusive evidence that taking over-the-counter anti-inflammatory drugs is harmful for other respiratory infections.”

https://www.healthline.com/health-news/what-to-know-about-ibuprofen-and-covid-19

It's a good thing that ibuprofen is not politically protected by lefties, otherwise you would not be able to find all this information on it. Especially not dissenting information.

[jimnyc]

It's a good thing that ibuprofen is not politically protected by lefties, otherwise you would not be able to find all this information on it. Especially not dissenting information.

And thankfully Trump never spoke highly of it being used or it might even be illegal by now!

[tailfins]

My wife got her 2nd shot (pfizer) yesterday at 3pm. Like the first, she got a bad vertigo vibe throughout the eve and didn't feel the greatest. But took a turn towards hell overnight like I did with my first. She was truly sick this morn and in tears. She's not too good with medications and avoids them like the plague. She did ultimately take a few Tylenol, and I shoved water on her to keep from dehydration. But you can tell it took it all out of her and she's got no energy and feels like the flu, but she has no temperature.

Pfizer is likely the best choice. I read somewhere that it's about to even be approved for children.

[xcz36]

So got my shot at 2pm, all fine for 5 minutes, then slightly light headed feeling and that was it til I left. Still a tad weird feeling, but no pain in the arm, no headache and no other symptoms. Probably light headed from coffee and no food!

Hopefully I won't develop a headache or fever. I can deal with the fever but tired of headaches.

And all they give you is a lame card? No signature? No raised stamp? Just a plain card from the CDC with my name filled in with pen and date & Pfizer vaccine. But no signature or anything like that. No wonder these idiots are worried about fraud, I could have made this card identically with a proper printer and card paper.

Now go back on the 18th for #2. :thumb:


Was just told spiritually that the so called vaccines ARE dangerous. I have no idea which ones though. Just want to warn everyone.

[jimnyc]

Was just told spiritually that the so called vaccines ARE dangerous. I have no idea which ones though. Just want to warn everyone.

Spiritually, huh? Thanks, I guess? :rolleyes: :laugh:

[Gunny]

Gunny's How To Deal with China flu shot #2:

Sprain your ankle the night before. Not a cheesy low ankle sprain either. High ankle sprain.

Just to make walking all the way to the back of Walgreens ro the pharmacy all the more pleasant:).

[Kathianne]

Gunny's How To Deal with China flu shot #2:

Sprain your ankle the night before. Not a cheesy low ankle sprain either. High ankle sprain.

Just to make walking all the way to the back of Walgreens ro the pharmacy all the more pleasant:).

:(

[jimnyc]

Gunny's How To Deal with China flu shot #2:

Sprain your ankle the night before. Not a cheesy low ankle sprain either. High ankle sprain.

Just to make walking all the way to the back of Walgreens ro the pharmacy all the more pleasant:).

They both made me sick as hell, but no migraine with the second at least.

Did you get the 2nd, or getting? Feel better if so!

[Gunny]

They both made me sick as hell, but no migraine with the second at least.

Did you get the 2nd, or getting? Feel better if so!
I haven't gotten full on sick. Got that "it's coming on" feeling 1st shot. Arm felt like I got hit with a hammer.

This one? Still waiting. Arm's a bit sore but not like the 1st. Only thing unusual is I went to bed on time and slept all night.

If it makes you feel better, my punk-ass bitch ankle hurts like Hell :)

[Abbey Marie]

Gunny's How To Deal with China flu shot #2:

Sprain your ankle the night before. Not a cheesy low ankle sprain either. High ankle sprain.

Just to make walking all the way to the back of Walgreens ro the pharmacy all the more pleasant:).

☹️

[fj1200]

Second shot last week. Maybe some soreness or I was sitting in a car for 6 hours the next day. :dunno:

[jimnyc]

Second shot last week. Maybe some soreness or I was sitting in a car for 6 hours the next day. :dunno:

Seems 50/50 if people get sick from it or not. And at least those that do recover awfully quickly.

'cept for those who croaked.

[fj1200]

Seems 50/50 if people get sick from it or not. And at least those that do recover awfully quickly.

'cept for those who croaked.

Yeah, I've heard of some people not feeling well for a few hours or day but that's about it from the people I know of. I'm guessing less than 50% but that's only anecdotal.

Ridiculously low mortality rate overall though. It's a wonder of a capitalist response to a problem.

[jimnyc]

Yeah, I've heard of some people not feeling well for a few hours or day but that's about it from the people I know of. I'm guessing less than 50% but that's only anecdotal.

Ridiculously low mortality rate overall though. It's a wonder of a capitalist response to a problem.

I was much worse off the 1st time but recovered fully by the end of the day. And the most difficult part only lasted a few hours or so. But it was still horrible. And do you know why? Because I'm a wuss!! :coffee:

My wife got sick only the 1st time, and nothing for my son. My Dad had no response but my step Mom was sick. :dunno:

[Tyr-Ziu Saxnot]

Seems 50/50 if people get sick from it or not. And at least those that do recover awfully quickly.

'cept for those who croaked.





'cept for those who croaked.

yep, it is those little minor details that really get ya.
Perhaps it is best to pretend those things dont exist..
You know, like how people pretend Covid-19 came in and somehow stopped all those deaths from the flu's and so many of the other old age related diseases..
Well hell, that is what the immensely and agenda driven fudged numbers show.
Else how else were they going to induce the much needed ever increasing fear-- that they wanted.
The fear that let them do so many other things- take away so many rights/freedoms and start a much better sheeple training program..
As if the public schools had not already been so very hugely successful in that arena!
And there ya have it- that damn cold hard truth that the usual dem/lib/leftist assholes so dearly hate....-Tyr

[gabosaurus]

My husband and I got our shots fairly early. Never had any ill effects. I am sure there have been some. Out of untold millions of shots administered everyone, there will be side effects and deaths. I have never understood why the mass suspicion and apprehension about the vaccines. I would say that it originated with a certain powerful political figure who was against it. Not something a manly man would submit to. Of course, there were similar uprisings against vaccines for polio, diphtheria, TB, Ebola and others. Should we shun those as well?

[jimnyc]

My husband and I got our shots fairly early. Never had any ill effects. I am sure there have been some. Out of untold millions of shots administered everyone, there will be side effects and deaths. I have never understood why the mass suspicion and apprehension about the vaccines. I would say that it originated with a certain powerful political figure who was against it. Not something a manly man would submit to. Of course, there were similar uprisings against vaccines for polio, diphtheria, TB, Ebola and others. Should we shun those as well?

I think it's mainly because it's a different type of vaccine & that it didn't go through the same rigorous testing. That, coupled with the mystery in China of exactly where this emanated from. I think that's great reason to be abundantly cautious about things. At the same time, when it comes to health and pandemics, we sometimes simply have faith in our doctors and medicine community.

It's difficult to compare uprisings or whatever about a vaccine during the time it comes out, compared to looking at things upon reflection. Of course we shouldn't shun those vaccines, but that doesn't take away from initial fears and people wanting full understanding before putting something in their bodies. In the end I choose vaccine safety, but I fully understand the hesitance of others.

[Tyr-Ziu Saxnot]

I think it's mainly because it's a different type of vaccine & that it didn't go through the same rigorous testing. That, coupled with the mystery in China of exactly where this emanated from. I think that's great reason to be abundantly cautious about things. At the same time, when it comes to health and pandemics, we sometimes simply have faith in our doctors and medicine community.

It's difficult to compare uprisings or whatever about a vaccine during the time it comes out, compared to looking at things upon reflection. Of course we shouldn't shun those vaccines, but that doesn't take away from initial fears and people wanting full understanding before putting something in their bodies. In the end I choose vaccine safety, but I fully understand the hesitance of others.

There are a helluva lot more reasons not to take the damn shot than there are to take it.
One informed look at the true death rate proves that- as well as all the damn lies they told to gin up fear!
And all the damn lies that they are still telling.--Tyr